The forgotten Hormone
HISTORY OF THE USE OF RELAXIN
Outside the United States, the use of Relaxin can be traced back thousands of years to the Chinese culture where the consumption of certain pig organs, high in Relaxin, was used to reinvigorate human organs and to promote good health. Relaxin was first discovered and investigated in the United States in 1926, when Frederick Hisaw, a soon to be Harvard researcher, reported the muscular relaxation benefits of porcine Relaxin injections in female guinea pigs. Relaxin was identified as a polypeptide hormone belonging to the insulin family and has been found in females of all species studied.
During the 1950s and 1960s there were several brand of FDA approved porcine Relaxin, which sold under the brand names Lutresin, Cervilaxin and Releasin. They were used extensively for such conditions as cervical ripening, premature labor, in vitro fertilization, pulmonary fibrosis, peripheral arterial disease, glaucoma and scleroderma.
In 1962, the Kefauver-Harris Drug Amendments mandated that all FDA approved pharmaceutical products, in addition to being safe, had to prove efficacy. Since porcine Relaxin had been used safely and effectively for 18 years, and because of the expense in conducting clinical studies to prove efficacy, the company that produced Lutresin chose to circumvent the mandate by taking the FDA to court. The company ultimately lost this legal battle and as a result, porcine Relaxin and many other drugs were taken off the market in 1972 due to unsubstantiated efficacy, not safety issues.
BACKGROUND OF RELAXIN
Relaxin (porcine), a polypeptide hormone belonging to the insulin family, was first discovered in the United States in 1926 and today over 1,500 research articles have been published on its impact on human physiology. Despite this body of evidence, porcine Relaxin has been virtually ignored in the United States due to a lack of communication between the scientific and medical communities and due to changes in pharmaceutical economics as a result of the 1962 Kefauver-Harris Drug Amendments.
During the 1990’s, Dr. Yue observed that many of his female patients with multiple health issues (fibromyalgia) reported their symptoms began or worsened after menopause or hysterectomies. These patients also reported that their symptoms went into remission during pregnancy, but returned one or two months after delivery. Dr. Yue was intrigued by these reports and began to look for a substance produced naturally in the body that would account for his observations. Initial research focused on the two most well known female hormones: estrogen and progesterone. However, no link was established.
Dr. Yue continued his research which ultimately pointed to the hormone Relaxin. During pregnancy Relaxin production increases almost 10-fold while following menopause or hysterectomy Relaxin levels are dramatically reduced. While Dr. Yue initially focused on the benefits of using Relaxin to treat his fibromyalgia patients, his continuing research indicated Relaxin has been shown to be beneficial for the treatment of a wide range of health and wellness issues. Some major chronic diseases like diabetes, peripheral vascular, psoriasis, all seems to have benefited after treatment of relaxin.
Dr. Sam Yue after reading over 1,500 scientific research papers and spent over 10 years treating more than 3,000 patients with Relaxing therapy with positive results. This results are shared with many physicians that have [Read more...]